Vick is in a must do well situation, he needs to limit the turnovers. I know you Eagles fans have heard that for the past 2 years, but they do. Also they need to run the football more with Lesean McCoy, who only rushed a total of 13 times last week which is unacceptable when you have one of the best football players in the NFL today.
King Dunlap will be out and Demetress Bell will get the start and this is a big game for him, if he can play well he can beat out Dunlap since the Eagles brought him in to start in the first place.
As for the defense Hakeem Knicks will not be playing, which is a plus for the secondary, but they still need to focus on Ramsees Barden who had a monster game last thursday night racking up over 100 yards receiving.
For me I believe you put DRC on Victor Cruz the whole game even if he is in the slot. The Eagles last week made the mistake of putting Boykin on Fitzgerald when he was in the slot, to me Nnamdi should have been on him the entire time no matter where he is. That is what they need to do this week keep DRC on Cruz the whole game and have Nnamdi take Barden and maybe even Tight End Martellus Bennett some of the time.
Prediction: I think the Eagles will take this one in a close game 20-17 at home with the crowd pumped about Dawkins jersey retirement and much more.